Remo Stars lost 1-0 to Medeama SC of Ghana in the CAF Champions League preliminary round fixture at the Cape Coast Stadium on Sunday night.
Medeama dominated the first leg encounter and would have scored more goals but for their poor marksmanship.
The home team took the lead through Jonathan Sowah in the 21st minute.
Sowah beat goalkeeper Kayode Bankole with a superb long range shot.
Daniel Ogunmodede’s side will need to score two goals without conceding in the reverse fixture to scale through.
The second leg is slated for the Remo Stars Stadium on Sunday, August 28.
